Friday, June 28, 2013

Peer Reviewed Studies Showing the Relationship between Acne and High Glycemic Diets, Dairy and Insulin-like Growth Factor 1.

Here's a list of Peer Reviewed Studies and Papers that Illustrate the Relationship between Diet and Acne.


Role of insulin, insulin-like growth factor-1, hyperglycaemic food and milk consumption in the
pathogenesis of acne vulgaris http://www.ncbi.nlm.nih.gov/pubmed/19709092

Takeaway:  The hormone IGF-1 is stimulated by insulin and in dairy and is a major factor in acne formation.


Short-term isotretinoin treatment decreases insulin-like growth factor-1 and insulin-like growth factor binding protein-3 levelshttp://www.ncbi.nlm.nih.gov/pubmed/20128787

Takeaway: Isotretinoin, aka Accutane,  works by decreasing IGF-1, which you could instead reduce by avoiding a high glycemic diet and by limiting dairy neither of which have dangerous side effects.

 Insulin & Glucose role on Sex Hormone production http://www.ncbi.nlm....ist_uids=193114  

This is a study on men with heart disease, but resulted in one of the earlier discoveries in the relation ship between insulin and hormones.  

Takeaway:  Insulin and glucose stimulate hormone production. Excess insulin and glucose means excess hormones. 

Acne in Adolescence and Cause-specific Mortality: Lower Coronary Heart Disease but Higher Prostate Cancer Mortality  (Scary title, I know).  http://aje.oxfordjournals.org/content/161/12/1094.full

This is a Study on the relationship between acne and prostrate cancer. Because many of the same hormones, IGF1 and Androgens are involved in both conditions.   The researchers discuss the role of diet on these hormones

Diet, serum insulin-like growth factor-I and IGF-binding protein-3 in European women
http://www.nature.co...s/1602494a.html

Takeaway: Once again, another study finds diet affects the hormones involved in acne.


Decreased serum insulin-like growth factor I response to growth hormone in hypophysectomized rats fed a low protein diet: evidence for a postreceptor defect
http://www.eje-onlin...tract/117/3/320

Diet, insulin-resistance and chronic inflammation
http://www.tifn.nl/w...a...A009&Prog=A

Acne and chronic inflammation (and Delayed Type Hypersensitivity (allergy)
http://www.ncbi.nlm....pubmed/15688807
http://www.ncbi.nlm....t...h&db=pubmed

Inflammation and insulin resistance
http://www.pubmedcen...i?artid=1483173
http://www.scienceda...71106133106.htm
http://www.pubmedcentral.nih.gov/articlere...$=activity

There's a growing renewed interest in the diet acne connection and that in addition to studies on acne, they utilize data on other conditions with known connections to the factors involved in acne:
http://www.medscape....rticle/579326_1

Other article summarizing some connections
http://www.cancersup.....Diet Acne.pdf


Study on diet affecting PMS
http://www.greenjour...t/full/95/2/245

For Mor: 
http://www.acne.org/messageboard/topic/230714-good-things-for-the-many-factors-that-lead-to-acne/page-2#entry2637530

4 comments:

  1. Should there be another persuasive post you can share next time, I’ll be surely waiting for it. Dermatologia

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  2. What an informative and incredibly helpful post thanks for sharing your experiences! Acne Scar Treatment Delhi

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    1. Thank You. This post is far from complete. There are so many more ways that diet impacts acne and other skin conditions.

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